佩戴角膜塑形镜与框架眼镜控制儿童近视效果及安全性比较

目的 比较儿童佩戴角膜塑形镜和框架眼镜两种方法控制近视的效果及安全性。方法 回顾性分析佩戴角膜塑形镜或框架眼镜治疗近视的儿童的病例资料，共219例、396只眼，其中佩戴角膜塑形镜的患儿145例、277只眼，佩戴框架眼镜的患儿74例、119只眼。观察两组患儿戴镜1年后屈光度、眼轴长度、角膜内皮细胞的变化并进行比较。结果 戴镜1年后，角膜塑形镜组患儿的屈光度及屈光度变化量均小于框架眼镜组（-3.03±0.89）DS vs（-3.83±1.25）DS，（-0.84±0.90）DS vs（-1.83±0.71）DS，P均<0.05]。两组患儿戴镜1年后眼轴长度差异无统计学意义，但角膜塑形镜组患儿的眼轴长度延长量小于框架眼镜组，差异有统计学意义（0.14±0.15）mm vs（0.40±0.17）mm，P<0.05]；两组患儿的角膜内皮细胞面积和密度差异无统计学意义。结论 儿童佩戴角膜塑形镜1年可有效控制近视程度的增长，且对角膜功能无不良影响。

Comparison of efficacy and safety between wearing orthokeratology contact lens and frame glasses for control of child myopia

Objective To evaluate of the effect and safety of wearing orthokeratology contact lens or frame glasses for controlling myopia in children. Methods The clinical data from myopia children, who wore orthokeratology contact lens or frame glasses to control myopia, were analyzed retrospectively. Of 219 children (396 eyes), 145 children (277 eyes) wore orthokeratology contact lens, and 74 (119) frame glasses. The changes of diopter, axial length and corneal endothelial cells were observed and compared one year after treatment in the two groups. Results After wearing one year, the diopter and the variation of diopter were significantly less in the children wearing orthokeratology contact lens than those in the children wearing frame glasses (-3.03±0.89] DS vs-3.83±1.25] DS,-0.84±0.90] DS vs-1.83±0.71] DS; both P<0.05). There was no significant difference in the axial length between the children wearing orthokeratology contact lens and frame glasses. While the extension of axial length was significantly less in the children wearing orthokeratology contact lens than that in the children wearing frame glasses (0.14±0.15] mm vs0.40±0.17] mm, P<0.05). No significant differences in the area or density of corneal endothelial cells were found between the children wearing orthokeratology contact lens and frame glasses. Conclusion Wearing orthokeratology contact lens can effectively control myopia in children within one year, and it had no adverse effects on corneal function.