| Ommaya储液囊植入术治疗隐球菌性脑膜炎临床观察 |
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| 引用本文： | 陈良义,郑维红,葛华.Ommaya储液囊植入术治疗隐球菌性脑膜炎临床观察[J].中国实用神经疾病杂志,2011,14(17):15-17. |
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| 作者姓名： | 陈良义 郑维红 葛华 |
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| 作者单位： | 厦门大学附属中山医院神经内科,厦门,361004 |
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| 摘 要： | 目的观察Ommaya储液囊植入术治疗隐球菌性脑膜炎的临床疗效。方法回顾性分析我院2002—2010年收治的27例隐球菌性脑膜炎患者临床资料,其中Ommaya储液囊治疗组10例,采用两性霉素B、氟康唑治疗、Ommaya储液囊治疗。非Ommaya储液囊治疗对照组17例,只给予两性霉素B+氟康唑治疗。结果 Ommaya储液囊治疗组隐球菌转阴时间(20±8)d,明显短于对照组的(35±10)d,两者比较差异具有统计学意义(P<0.05)。Ommaya储液囊治疗组治愈率60.0%,总有效率90.0%,病死率10.0%,好于对照组(治愈率29.4%,总有效率47.1%,病死率17.6%),两者疗效比较差异有统计学意义(P<0.05)。结论植入Ommaya储液囊能有效改善症状,减少并发症,提高治愈率、好转率,降低病死率,值得临床进一步推广。
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| 关 键 词： | 隐球菌性脑膜炎 Ommaya储液囊 |
Clinical observation on Ommaya reservoir implantation in the treatment of cryptococcosis meningitis |
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| Chen Liangyi,Zheng Weihong,Ge Hua.Clinical observation on Ommaya reservoir implantation in the treatment of cryptococcosis meningitis[J].Chinese Journal of Practical Neruous Diseases,2011,14(17):15-17. |
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| Authors: | Chen Liangyi Zheng Weihong Ge Hua |
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| Institution: | Chen Liangyi,Zheng Weihong,Ge Hua.Department of Neurolagy,Affiliated Xiamen Zhongshan Hospital to Xiamen University,Xiamen 361004,China |
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| Abstract: | Objective To investigate the clinical effect of Ommaya reservoir implantation in the treatment of cryptococcosis meningitis.Methods Twenty-seven patients with cryptococcosis meningitis were retrospectively studied.The Ommaya reservoir implantation group included 10 patients,who were treated with Amphotericin B,fluconazol and Ommaya reservoir implantation.The control group included 17 patients,who were treated with Amphotericin B and fluconazol.Results The period of cryptococcosis disappearance in the Ommaya... |
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| Keywords: | Cryptococcosis meningitis Ommaya reservoir |
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