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| 糖尿病患者义齿修复后龈沟液中白介素-1变化的实验研究 | |
| 引用本文： | 柳云霞,宋继武,刘宗霞,牟月照.糖尿病患者义齿修复后龈沟液中白介素-1变化的实验研究[J].口腔颌面修复学杂志,2010,11(4):204-206. |
| 作者姓名： | 柳云霞 宋继武 刘宗霞 牟月照 |
| 作者单位： | 1. 潍坊医学院口腔学院,山东,261053 2. 潍坊市人民医院牙科,山东,261041 3. 潍坊医学院口腔学院,山东,261041 4. 山东省立医院口腔科,山东,250012 |
| 基金项目： | 山东省科技发展计划项目 |
| 摘 要： | 目的：探讨糖尿病患者戴用可摘局部义齿后龈沟液中白介素-1（IL-1）的变化,从而为临床上糖尿病患者义齿修复方式的选择提供依据。方法：对牙列缺损的糖尿病患者进行钴铬合金铸造支架式可摘局部义齿修复,在修复后六个月时分别采取基牙和非基牙区的龈沟液,用酶联免疫吸附法测定分析IL-1的表达水平。结果：可摘局部义齿修复后,糖尿病患者近缺隙侧基牙区龈沟液中IL-1的表达水平明显升高,而非基牙区则无明显改变。结论：糖尿病患者可摘局部义齿修复对基牙龈沟液中IL-1的表达水平有影响,从而为临床义齿修复提供了一定的理论依据。 |
| 关 键 词： | 糖尿病 可摘局部义齿 龈沟液 白细胞介素-1 |
The investigation to changes of IL-1 in gingival crevicular fluid after using RPD |
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| LIU Yun-xia,SONG Ji-wu,LIU Zong-xia,Mou Yue-zhao.The investigation to changes of IL-1 in gingival crevicular fluid after using RPD[J].Chinese Journal of Prosthodontics,2010,11(4):204-206. | |
| Authors: | LIU Yun-xia SONG Ji-wu LIU Zong-xia Mou Yue-zhao |
| Institution: | .(Weifang Medical University Shandong 261053,China) |
| Abstract: | Objective：To investigate the changes of IL-1 in gingival crevicular fluid （GCF） after diabetic patients using removable partial denture（RPD）,So offer support for the clinical application.Methods： After six months for the Co-Cr RPD finished,the GCF was collected from the gingival crevice.The concentrations of IL-1 in different patients were deter-mined by enzyme-linked immuno-sorbent assay（ELISA） and comparaed.Results： For the IL-1 of GCF to abutment,the IL-1 concentrations were higher than before and higher than that of non-abutments after six months.Conclusion： The IL-1 concentrations in GCF of abutments are influenced by RPD,so offer support for the clinical application. |
| Keywords: | diabetes RPD GCF IL-1 |
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