两种浓度氟保护漆在体外对变形链球菌、远缘链球菌生长抑制作用的实验研究

目的 比较两种浓度氟保护漆对致龋链球菌生长抑制作用.为推广氟保护漆进行群体防龋提供可靠的理论依据.方法 将实验组:0.5%氟保护漆、0.1%氟保护漆;对照组:0.1%洗必泰、0.05%氟化钠、0.9%生理盐水分别加入含有变形链球菌、远缘链球菌菌悬液的BHI培养基中,采用厌氧连续培养技术,观测菌落计数变化.比较其对致龋链球菌生长抑制作用效果.结果 0.5%氟保护漆、0.1%氟保护漆对致龋链球菌具有一定的抑制作用,但是其作用明显小于0.1%洗必泰.二者之间抑制生长效果存在显著性差异.结论 两种浓度氟保护漆在体外能直接杀灭一定数量的致龋链球菌.

Experimental study on growth inhibition of two different concentrations fluoride protectors to Streptococcus mutans and Streptococcus sobrinus

Objective To compare the growth inhibiting effect of two different concentrations fluoride protectors to Streptococcus mutans and Streptococcus sobrinus. To provide reliable theoretic evidence to fluoride protector for population to prevent dental caries. Methods To put 0.5% fluoride protector,0. 1% fluoride protectors for the experiment groups and 0. 1 % chlorhexidine, 0.05% sodium fluorideide, 0.9%normal sodium for the control groups into BHI nutritive medium with Streptococcus mutans and Streptococcus sobrinus suspension. The technique of continuous cultivation was adopted, and the change of colony count was observed. To compare the growth inhibiting effects of Streptococcus mutans and Streptococcus sobrinus. Results 0.5% fluoride protector and 0.1 % fluoride protectors could kill Streptococcus mutans and Streptococcus sobrinus in certain degree. But their effect was much smaller than 0.1%chlorhexidine effect. There was significant difference between them in growth inhibiting effect. Conclusion Two different concentrations fluoride protectors could kill certain quantitative Streptococcus mutans and Streptococcus sobrinus in vitro.