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Kawasaki Disease update
Authors:Jane C. Burns
Affiliation:(1) Departments of Pediatrics, UCSD School of Medicine, Rady Children’s Hospital, La Jolla, CA 92093, USA;(2) Division of Allergy, Immunology, and Rheumatology, Director, Kawasaki Disease Research Center, Dept. of Pediatrics 0641, UCSD School of Medicine and Rady Children’s Hospital, 9500 Gilman Dr., La Jolla, CA 92093-0641, USA
Abstract:Kawasaki Disease is rapidly becoming the most common cause of acquired heart disease in children in both the developed and developing world. Its etiology remains a mystery but important progress has been made in characterizing the features of the arterial wall and myocardial pathology and long-term clinical consequences. New treatments aimed at modifying the host immune response are currently under study. The genetic influence on susceptibility and disease outcome is an area of active research.
Keywords:Kawasaki disease  Vasculitis  Coronary artery aneurysms  Myocardial infraction
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