| 无精和严重寡精症中无精子症因子基因的初步研究 |
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| 引用本文： | 赵亚力 谈代明. 无精和严重寡精症中无精子症因子基因的初步研究[J]. 军医进修学院学报, 1997, 18(4): 253-255 |
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| 作者姓名： | 赵亚力 谈代明 |
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| 作者单位： | 解放军总医院分子生物学研究室 |
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| 摘 要： | 目的：研究无精子症因子基因与无精症的关系。方法：利用聚合酶链反应对７４例原发无精和严重寡精患者进行ＹＲＲＭ基因的扩增检查，同时利用男性性别决定的ＳＲＹ基因片段作为内参照系统。结果：在检查的７４例病例中，共有４例的ＹＲＲＭ基因位点没有扩增信号。结论：提示这些个体带有ＹＲＲＭ的缺失异常，与无精所致的不育直接相关。
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| 关 键 词： | 男性 不育症 无精子症 寡精症 基因 |
Studies on YRRM gene in azoospermia and severe oligospermia |
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| Zhao Yali,Tan Daiming,Gu Zhiyuan,Li Yunlian,Ma Junlong. Studies on YRRM gene in azoospermia and severe oligospermia[J]. Academic Journal of Pla Postgraduate Medical School, 1997, 18(4): 253-255 |
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| Authors: | Zhao Yali Tan Daiming Gu Zhiyuan Li Yunlian Ma Junlong |
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| Abstract: | Objective:Study the relationship between the AZF gene and azoospermia. Methods:Using the PCR method, we analyzed YRRM gene (the candidates gene for AZF, Azoospermia Factor) from 74 Chinese men with either azoospermia or severe oligospermia. The SRY gene was used for internal control. Results:4 of 74 men have no amplification band in the YRRM gene. Conclusion:It suggested that these case with abnormal YRRM gene may be result in the male infertility. |
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| Keywords: | male infterlity PCR azoospermia |
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