| 吗啡依赖性大鼠海马CA1区NKB细胞的改变 |
| |
| 引用本文： | 周郦楠,王冶,张广新. 吗啡依赖性大鼠海马CA1区NKB细胞的改变[J]. 解剖与临床, 2004, 9(4): 244-246 |
| |
| 作者姓名： | 周郦楠 王冶 张广新 |
| |
| 作者单位： | 辽宁中医学院职业技术学院形态教研室,辽宁沈阳,110101 |
| |
| 基金项目： | 辽宁省教育厅资助项目编号202153324 |
| |
| 摘 要： | 目的观察吗啡依赖性大鼠海马CA1区NKB细胞的变化.方法用皮下注射吗啡法建立雄性大鼠吗啡依赖模型.用免疫组织化学和图像分析方法观察大鼠CA1区NKB细胞的变化.结果吗啡依赖性大鼠海马CA1区NKB细胞免疫反应减弱,与对照组相比差异显著(P＜0.01).结论NKB细胞减少与吗啡依赖性的发生、发展有关.
|
| 关 键 词： | 吗啡依赖 大鼠 海马CA1区 NKB细胞 免疫反应 |
| 修稿时间： | 2004-05-13 |
The Alteration of NKB in CA1 of Hippocampus in Morphine Dependent Rats |
| |
| Zhou Linan,Wang Ye,Zhang Guangxin. The Alteration of NKB in CA1 of Hippocampus in Morphine Dependent Rats[J]. Anatomy and Clinics, 2004, 9(4): 244-246 |
| |
| Authors: | Zhou Linan Wang Ye Zhang Guangxin |
| |
| Abstract: | Objective:To investigate the relationship between changes of NKB and morphine dependence in rats.Methods:The morphine dependent model of male rats was made by subcutaneous injection of morphine.The alteration of NKB in the hippocampus CA 1 neuron of the rats were studied by means of immunohistochemical method and micro-image analysis system.Results:The NKB positive reactive product in the experiment group was lower than that in the control group ( P <0.01).Conclusion:NKB may play an important role in maintenance and development of morphine dependence. |
| |
| Keywords: | Morphine dependence Hippocampus Neuropeptide B Rat |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
