通过杀菌试验观察隐形眼镜护理液杀菌活性成分的吸附作用

目的：为观察隐形眼镜护理液杀菌活性成分的吸附作用。方法：采用悬液定量杀菌试验方法。结果：对分别含0．00014％西吡氯铵（CPC）和含0．0001％聚亚已基缩二胍（PHMB）的两种隐形眼镜护理掖进行杀菌试骏。结果显示：（1）对含0．00014％西吡氯铵（CPC）的护理液．作用时间6h：用经护理液样品预处理过的玻璃和塑料试管进行试验，对金黄色葡萄球菌．大肠杆菌、绿脓杆菌三种细菌的平均杀灭率在99．90％以上；而用未经护理液样品预处理过的玻璃和塑料试管进行试验，对三种细菌的平均杀灭率在99．90％以下。试管处理与否对三种细菌的杀菌效果存在明显差异。（2）对含0.0001％聚亚已基双胍（PHMB）的护理液，作用时间4小时：塑料试管处理与否对三种细菌的杀菌效果无明显差异；玻璃试管处理与否对金黄色葡萄球菌和大肠杆菌的杀菌效果有影响。结论：玻璃和塑料试管壁对CPC都有吸附作用。玻璃试管对PHMB有少量吸附作用。

The Sorption Was Observed on the Active Ingredient of Contact Lens Care Solution by Germicidal Test

Objective: In order to observe the sorption on the active ingredient of contact lens care solution. Method: Suspension quantitative germicidal test method was carried out. Result: The germicidal tests were carried out for two contact lens care solutions containing 0.00014%CPC and 0.0001%PHMB respectively. The results showed: 1. For the contact lens care solution containing 0.00014%CPC with 6 hours exposure time: The average killing rates of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were over 99.90% using the glass and plastic test tubes preconditioned with the test sample, and were below 99.90% using the glass and plastic test tubes not preconditioned with the test sample. There were obvious differences in eff icacy of killing three bacteria whether the test tubes were preconditioned. 2. For the contact lens care solution containing 0.0001%PHMB with 4 hours exposure time: No obvious difference in eff icacy of killing three bacteria whether the plastic test tubes were preconditioned. There were in? uences in eff icacy of killing Staphylococcus aureus and Escherichia coli whether the glass test tubes were preconditioned. Conclusion: The wall of the glass and plastic test tube has sorption to CPC. The wall of the glass test tube has slight sorption to PHMB.