Objective To study the chemical constituents of Swertia cincta.Methods Preparative liquid chromatography was employed.The structures of the compounds were elucidated by spectroscopic analysis.Results Three secoiridoid glycosides were isolated from S.cincta and identified as 8-methoxyl-eustomorusside(1),secoiridoids eustomorusside(2),and eustomoside(3).Conclusion Compound 1 is a new secoiridoid glycoside.Compounds 2 and 3 are isolated from this plant for the first time.