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Unconscious Confusion
Authors:Roland D. Thijs MD  David G. Benditt MD   FACC   FRCP   Christopher J. Mathias MD   DPhil   DSc   FRCP   FMedSci  Ronald Schondorf MD   PhD  Richard Sutton DScMed   FRCP   FESC   FACC  Wouter Wieling MD   PhD  J. Gert van Dijk MD   PhD
Affiliation:(1) Dept. of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, 9600, 2300 RC Leiden, The Netherlands;(2) Cardiovascular Division, University of Minnesota, Minneapolis (MN), USA;(3) Neurovascular Medicine Unit, Faculty of Medicine, Imperial College London at St Mary"rsquo"s, London, UK;(4) Autonomic Unit National, Hospital for Neurology and Neurosurgery at Queen Square, University College London, London, UK;(5) Autonomic Reflex Laboratory, Dept. of Neurology McGill University, Lady Davis Institute, Sir Mortimer B. Davis Jewish General Hospital, Montreal (QC), Canada;(6) Dept. of Cardiology, Royal Brompton Hospital, London, UK;(7) Dept. of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Abstract:Abstract Background Imprecise definitions of syncope and related conditions appear common in the medical literature. To investigate the scope of the problem we systematically searched for definitions in high-ranking medical journals. Methods Literature review of articles on lsquosyncopersquo, lsquoneurocardiogenic syncopersquo, lsquoneurally mediated syncopersquo, lsquoorthostatic intolerancersquo, and lsquoorthostatic hypotensionrsquo with these keywords in the title, mainly published in the ten journals with the highest impact in the fields of cardiology, internal medicine, and neurology. Results Syncope, neurocardiogenic syncope, neurally mediated syncope, orthostatic intolerance, and orthostatic hypotension were defined in only 41%, 34%, 26%, 38%, and 48% of papers respectively. Definitions, when given, differed considerably among papers. Orthostatic hypotension was most frequently defined, with an increase in number and consistency of definitions after publication of a consensus in 1996. Conclusions Syncope and related conditions proved to be infrequently and inconsistently defined in current medical literature. The lack of consistent terminology is likely to harm medical education, research, and patient care. There is a strong need for a systematic terminology for syncope and related conditions.
Keywords:syncope  orthostatic hypotension  orthostatic intolerance  terminology  definition
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