Identification of the products of the equine herpesvirus type 4 gI and gE genes |
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| Authors: | A M Damiani T Matsumura H-K Jang Y Izumiya T Mikami E Takahashi |
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| Institution: | (1) Department of Veterinary Microbiology, Faculty of Agriculture, The University of Tokyo, Tokyo, Japan, JP;(2) Epizootic Research Station, Equine Research Institute, The Japan Racing Association, Tochigi, Japan, JP;(3) Department of Microbiology and Immunology, Louisiana State University Medical Center, Shreveport, Louisiana, U.S.A., US;(4) The Research Center for Protozoan Molecular Immunology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan, JP |
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| Abstract: | Summary. In order to identify the products of the equine herpesvirus type 4 (EHV-4) gI and gE genes, we have constructed recombinant
vaccinia viruses containing the putative gI or gE genes. These recombinant viruses synthesized EHV-4 gI and gE with apparent
molecular masses of 75 and 80 kDa, respectively. Antibodies raised against both recombinant viruses detected a 75 kDa gI and
a 95 kDa gE in EHV-4-infected cells. The results also suggest that the EHV-4 gI and gE would form a complex like in other
herpesviruses.
Received October 29, 1999 Accepted January 21, 2000 |
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