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神经内分泌拮抗剂治疗心力衰竭的研究进展
引用本文:陈瑞玲 赵志刚. 神经内分泌拮抗剂治疗心力衰竭的研究进展[J]. 中国临床药理学杂志, 2006, 22(4): 307-309
作者姓名:陈瑞玲 赵志刚
作者单位:首都医科大学附属北京天坛医院药剂科,北京100050
摘    要:慢性心力衰竭(CHF)发病率和死亡率均很高,内分泌激活是其重要特点,神经内分泌拮抗剂对CHF治疗作用,本文对其临床研究做一综述.

关 键 词:慢性心力衰竭  神经内分泌拮抗剂
文章编号:1001-6821(2006)04-0307-03
收稿时间:2006-01-05
修稿时间:2006-01-052006-05-07

Progress of neureurohormonal antagonists in the treatment of chronic heart failure
CHEN Rui-ling,ZHAO Zhi-gang. Progress of neureurohormonal antagonists in the treatment of chronic heart failure[J]. The Chinese Journal of Clinical Pharmacology, 2006, 22(4): 307-309
Authors:CHEN Rui-ling  ZHAO Zhi-gang
Affiliation:Department of Pharmacy, Belting Tiantan Hospital, Capital University of Medical Sciences, Beijing 100050, China
Abstract:Chronic heart failure (CHF)is described as a clinical syndrome with high morbidity and mortality. In general,the pathophysiolo- gic mechanisms is responsible for cardiac remodeling and characterized by neuroendocrine activation.It shown that the neurohormonal antagonists had clinical efficacy in the treatment of CHF. We review some neurohormonal antagonists for CHF therapy, to provide reference for clinical parmacological therapies.
Keywords:chronic heart failure   pharmacological therapies neurohormonal antagonists
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