| 加味补肾利湿汤配合虫类药治疗慢性肾炎蛋白尿的临床观察 |
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| 引用本文： | 赵文景,张炳厚,刘宝利等.加味补肾利湿汤配合虫类药治疗慢性肾炎蛋白尿的临床观察[J].北京中医药,2014(3):179-181,183. |
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| 作者姓名： | 赵文景 张炳厚 刘宝利等 |
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| 作者单位： | 首都医科大学附属北京中医医院肾病科中国中医科学院博士后科研流动站,北京100010 |
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| 摘 要： | 目的观察虫类药配合张炳厚教授经验方加味补肾利湿汤治疗慢性肾小球肾炎蛋白尿的疗效及安全性。方法按照随机分组原则，将64例慢性肾炎蛋白尿患者分为对照组和治疗组各32例，对照组仅予加味补肾利湿汤辨证治疗；治疗组在对照组治疗基础上加龟甲、蝉蜕、僵蚕、水蛭、全蝎、地龙、穿山甲，2组均治疗8周后观察中医证候积分、24h尿蛋白定量及肝肾功能等变化。结果2组治疗后中医证候积分均较治疗前下降，差异有统计学意义（P〈0．01），但2组间比较差异无统计学意义。2组治疗后24h尿蛋白定量均较治疗前下降，差异有统计学意义（P〈0．01）；治疗组下降较对照组更为明显，差异有统计学意义（P〈0．01）。治疗过程中，2组患者生命体征平稳，复查血、尿、便常规及肝肾功能稳定，心电图及腹部超声较治疗前无明显动态变化。结论加味补肾利湿汤能够明显改善慢性肾炎蛋白尿患者症状，配合虫类药可更为有效地减少蛋白尿，安全性好。
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| 关 键 词： | 慢性肾炎蛋白尿 虫类药 加味补肾利湿汤 |
Clinical observation of Modified Tonifying-kidney and Eliminating-dampness Decoction combined with medicinal insects on treatment of proteinuria in chronic nephritis |
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| ZHAO Wen-jing,ZHANG Bing-hou,LIU Bao-li,ZHANG Sheng-rong,SUN Ming-xia,DUAN Yu-fang,ZHAO Kai-sheng,CAI Zhen,MENG Yuan,ZHAO Jing.Clinical observation of Modified Tonifying-kidney and Eliminating-dampness Decoction combined with medicinal insects on treatment of proteinuria in chronic nephritis[J].Beijing Journal of Traditional Chinese Medicine,2014(3):179-181,183. |
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| Authors: | ZHAO Wen-jing ZHANG Bing-hou LIU Bao-li ZHANG Sheng-rong SUN Ming-xia DUAN Yu-fang ZHAO Kai-sheng CAI Zhen MENG Yuan ZHAO Jing |
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| Institution: | ( Department of Nephropathy, Belling TCM Hospital Affiliated to Capital Medical University, Center for Post-Doctoral Studies, Beijing 100010, China) |
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| Abstract: | |
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| Keywords: | medicinal insects proteinuria in chronic nephritis Modified Tonifying-kidney and Eliminating-dampness Decoction |
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