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肾脏疾病患者血中泌乳素、促黄体生成素、促卵泡刺激素及睾丸酮的改变
引用本文:田浩明,梁荩忠,马行一,余庭龙,杨立川,邱东生.肾脏疾病患者血中泌乳素、促黄体生成素、促卵泡刺激素及睾丸酮的改变[J].四川大学学报(医学版),1992(1).
作者姓名:田浩明  梁荩忠  马行一  余庭龙  杨立川  邱东生
作者单位:华西医科大学内分泌科 (田浩明,梁荩忠),华西医科大学肾脏内科 (马行一,余庭龙,杨立川),华西医科大学妇产科内分泌实验室(邱东生)
摘    要:作者测定了41例不同程度肾功能损害的肾脏疾病患者(男22,女19)血清PRL水平,同时测定了男性患者的FSH,LH、T水平,并与20例同龄男性正常人PRL、LH、FSH、T水平进行了比较。结果发现肾脏疾病患者PRL水平升高,其中尿毒症期患者PRL升高显著。男性尿毒症患者除PRL水平明显升高外,LH也有升高,T水平则明显降低,且与肾功能损害程度有关。PRL水平与T水平呈负相关。5例男性尿毒症患者CAPD后未发现PRL、LH、FSH、T水平有明显变化。

关 键 词:尿毒症  泌乳素  促黄体生成素  促卵泡刺激素  睾丸酮

The Variations of PRL, LH, FSH and Testosterone in Renal Disease
Tian Haoming,Liang Jinzhong,Ma Xingyi,Yu Tinglong,Yang Lichuan,Qiu Dongsheng.The Variations of PRL, LH, FSH and Testosterone in Renal Disease[J].Journal of West China University of Medical Sciences,1992(1).
Authors:Tian Haoming  Liang Jinzhong  Ma Xingyi  Yu Tinglong  Yang Lichuan  Qiu Dongsheng
Institution:Tian Haoming,Liang Jinzhong,Ma Xingyi,Yu Tinglong,Yang Lichuan,Qiu Dongsheng Department of Medicine,The First Affiliated Hospital Laboratory of Endocrinology,The Second Affiliated Hospital
Abstract:Blood PRL was measured withRIA in 22 males and 19 females with vari-ous degrees of renal insufficiency. At thesame time, blood LH, FSH, testosterone werestudied in all the male patients and 20 sex-age matched healthy subjects. The resultsshowed that the levels of PRL and LH wereincreased, and the level of testosterone wasdecreased significantly in male uremic pa-tients. There was a signifcant negative cor-relation between PRL and testosterone. All the above parameters were measur-ed again 8-25 days after continuous ambu-latory peritoneal dialysis (CAPD) therapyin 5 male uremic patients. The BUN and Crlevels decreased and the clinical manifes-tations of uremia improved. but the levelsof PRL, LH,FSH and testosterone showedno significant changes. The mechanisms ofthese variations were discussed.
Keywords:Uremia  Prolactin  Luteinizing hormone  Follicle stimulating hormone  Testosterone  Renal disease
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