| 肿瘤坏死因子-α的放疗增敏机制 |
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| 引用本文： | 葛宜枝,汪步海,徐立春. 肿瘤坏死因子-α的放疗增敏机制[J]. 国际肿瘤学杂志, 2015, 42(1): 49-51 |
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| 作者姓名： | 葛宜枝 汪步海 徐立春 |
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| 作者单位： | 1. 225001,扬州大学医学院肿瘤防治研究中心
2. 江苏省苏北人民医院肿瘤科 |
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| 摘 要： | 肿瘤坏死因子-α (TNF-α)是一种具有广泛生物活性的细胞因子,与多种疾病的发生发展密切相关.目前已有较多学者使用TNF-α作为放疗增敏剂来研究其对肿瘤细胞放疗增敏的效果,研究发现其机制可能与细胞凋亡、细胞周期、乏氧细胞、DNA损伤修复等有关.
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| 关 键 词： | 肿瘤坏死因子-α 放射疗法 辐射增敏药 |
| 收稿时间： | 2014-06-10; |
Radiotherapy sensitization mechanisms of tumor necrosis factor-α |
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| Ge Yizhi , Wang Buhai , Xu Lichun. Radiotherapy sensitization mechanisms of tumor necrosis factor-α[J]. Journal of International Oncology, 2015, 42(1): 49-51 |
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| Authors: | Ge Yizhi Wang Buhai Xu Lichun |
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| Affiliation: | Center for Cancer Research on Prevention and Treatment, Medical College of Yangzhou University, Yangzhou 225001, China |
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| Abstract: | Tumor necrosis factor-α （TNF-α）is a kind of cytokines with a wide range of biological activity, which is closely related to the occurrence and development of various diseases. Nowadays, a number of researchers use TNF α as a radiation sensitizing agent to evaluate the effect of radiation sensitivity of tumor cells. The scheme may have correlation with cell apoptosis, cell cycle, hypoxic cells, repair of DNA damage, etc. |
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| Keywords: | Tumor necrosis factor-&alpha Radiotherapy Radiation sensitizing agents |
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