肠易激综合征患者胃肠运动功能的临床研究

目的：对16例肠易激综合征（IBS）患者胃肠运动功能进行临床分析，为临床研究肠易激综合征的发病机制及临床药物治疗提供理论依据。方法：对16例肠易激综合征患者进行食管动态pH监测、胃电检测和呼吸氢试验分析。结果：肠易激综合征患者进餐前、后胃电变化较对照组明显（t＝-8.437，t＝-7.126；P〈0.01），胃电变异指数、肠道传递时间与对照组有显著性差异（t＝-2.312，t＝-1.694，t＝-9.163，t＝-7.894；P〈0.01）。结论：肠易激综合征患者消化吸收及肠道运动功能异常可能是由于肠道电生理活动异常而引起。

Clinical analysis of 16 cases of irritable bowel syndrome of gastrointestinal motility function

Objective：To analyze irritable bowel syndrome of 16 cases of gastrointestinal motor function, and provide a theoretical basis for the clinical study on the pathogenesis of irritable bowel syndrome and clinical drug treatment. Methods： Patients in our hospital from 2009 to 2011 with irritable bowel syndrome of esophageal pH monitoring, gastric electrical detection and breath hydrogen test was performed in 16 patients. Results： the patients with irritable bowel syndrome before and after meal gastric electrical change significantly compared with the control group（t=-8.437, t=-7.126;P〈0.01）, gastric electrical variability index, intestinal transfer time and the control group with significant difference （t=-2.312, t=-1.694, t=-9.163, t=-7.894;P〈0.01）. Conclusion：The abnormal in patients with irritable bowel syndrome and intestinal digestion and absorption function may be caused by abnormal gut electrophysiological activity.