荨麻疹1000例变应原皮肤点刺试验结果分析

目的分析1000例荨麻疹患者应用点刺液变应原皮肤试验结果,为本地区荨麻疹的防治及点刺试验变应原的选择提供依据。方法用30种变应原,加一个生理盐水阴性对照和一个组胺阳性对照,试验部位是前臂掌侧皮肤,相距4 cm,滴1滴变应原后垂直点刺,20-30 min后判读试验结果。结果765例(76.5%)呈阳性。皮肤点刺试验中屋尘螨阳性率最高,其次是粉尘螨等。结论屋尘螨和粉尘螨是北京地区重要变应原。变应原皮肤点刺试验用于寻找荨麻疹患者的致病原因安全有效。

Allergen Analysis for 1000 Cases of Urticaria by Skin Prick Test

Objective To analyse the results of skin test for 1 000 cases of urticaria in which the standardized fluid was used as allergen for skin-prick testing,which provide a clue for prevention and cure for urticaria and selection of allergens used in diagnosis in the area.Methods Thirty kinds of allergens were used,and normal saline was used as negative control,while histamine was used as positive control.The testing place was on the skin of palmar in forearm,with a space of 4 cm.After dropping a drop of allergen fluid on the place,pricked it vertically,and 20-30 minutes later,the testing results were analysed.Results One thousand patients enrolled,765(76.5%) had positive results.Among the 765 positive patients,the positive rate of house dust mite was the highest,and flour mite was the second.Conclusion Our study shows that house dust mite and flour mite are the most common allergens in Beijing area.Skin-prick testing is effective and safe method to urticaria.