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| 壳聚糖胶原生物敷料的安全性研究 | |
| 引用本文： | 王晓芹,李晓辉,王贵波,王秀芹,唐渊,张海港,周见至. 壳聚糖胶原生物敷料的安全性研究[J]. 中国组织工程研究与临床康复, 2002, 6(7): 1030-1031 |
| 作者姓名： | 王晓芹 李晓辉 王贵波 王秀芹 唐渊 张海港 周见至 |
| 作者单位： | 1. 解放军第三军医大学药理教研室,重庆,400038 2. 解放军第三军医大学西南医院,重庆400038 3. 安丘市招待所医院,山东,安丘,262100 |
| 摘 要： | 目的研究壳聚糖胶原生物敷料(chitosan-collagenbiologicaldressing,CCBD)的生物安全性。方法通过CCBDA、B原液兔皮肤刺激实验、角结膜刺激实验、肌肉刺激实验和细胞毒性实验研究CCBDA、B的生物安全性。结果CCBDA、B原液无皮肤、角结膜和肌肉刺激性,对角质形成细胞和成纤维细胞无毒性。结论CCBDA、B具良好生物安全性。 |
| 关 键 词： | 壳聚糖 敷料 安全性 |
| 文章编号： | 1671-5926(2002)06-1030-02 |
| 修稿时间： | 2001-11-01 |
A study of reliability of Chitosan-Collagen biological dressing |
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| WANG Xiao qin,LI Xiao hui,WANG Gui bo,et al.. A study of reliability of Chitosan-Collagen biological dressing[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(7): 1030-1031 | |
| Authors: | WANG Xiao qin LI Xiao hui WANG Gui bo et al. |
| Affiliation: | WANG Xiao qin,LI Xiao hui,WANG Gui bo,et al.Third Military Medical University,Chongqing 400038,China |
| Abstract: | Objective To study the biological reliability of Chitosan Collagen Biological Dressing (CCBD).Method The biological reliability of CCBD A, B were studied by skin, cerato conjunctiva, muscle stimulating test and cytotoxicity test with pro fluids of CCBD A, B. Result Pro fluids of CCBD A,B were not stimulating in skin, cerato conjunctiva and muscle stimulating test. Pro fluids of CCBD A, B had not poisonous effect on keratinocytes and fibroblasts.Conclusion CCBD A, B have satisfactory reliabilities. |
| Keywords: | chitosan dressing reliability |
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