| 非ST段抬高急性冠状动脉综合征诊疗策略新进展 |
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| 引用本文： | 刘玲梅,张梅. 非ST段抬高急性冠状动脉综合征诊疗策略新进展[J]. 中国心血管杂志, 2006, 11(4): 311-314 |
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| 作者姓名： | 刘玲梅 张梅 |
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| 作者单位： | 1. 天津市海河医院,天津,300350
2. 天津医科大学第二医院,天津,300211 |
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| 摘 要： | 随着对非ST段抬高急性冠状动脉综合征病理生理机制理解的不断深入,使其治疗方式不断得到提高,临床预后不断得到改善。低分子肝素、血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂及早期再血管化治疗对高危的患者均显示出强大的临床益处,而氯吡格雷的益处似乎覆盖了所有的低、中、高危患者,直接凝血酶抑制剂的作用值得进一步探讨。危险分层策略是作出治疗决定的基础,为新治疗的选择提供了依据。
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| 关 键 词： | 急性冠脉综合征 抗凝 抗血小板 经皮冠状动脉介入治疗 危险分层 |
| 文章编号： | 1007-5410(2006)04-0311-04 |
| 收稿时间： | 2005-11-25 |
| 修稿时间： | 2006-01-17 |
Progress in diagnostic and therapeutic slrategy of non-ST elevation acute coronary syndromes |
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| LIU Ling-mei,ZHANG Mei. Progress in diagnostic and therapeutic slrategy of non-ST elevation acute coronary syndromes[J]. Chinese Journal of Cardiovascular Medicine, 2006, 11(4): 311-314 |
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| Authors: | LIU Ling-mei ZHANG Mei |
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| Affiliation: | Taijin Haihe Hospitel , Tianjin 300350; 2. Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, China |
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| Abstract: | With the increasing understanding in the pathophysiologic mechanisms of non-ST segment elevation acute coronary syndromes(NSTE ACS),therapeutic methods and clinical outcomes of the syndromes have been improved.Low-molecular-weight heparin,glycoprotein Ⅱb/Ⅲa receptor antagonist and early revascularization strategy have shown potential clinical benefit for high risk NSTE ACS patients,and the benefit of clopidogrel seems to cover all low-risk,intermediated-risk and high-risk NSTE ACS patients.The efficacy of direct thrombin inhibitors requires to be more discussed.Risk stratification is the basis of therapeutic decision and provide evidence for the selection of new therapy. |
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| Keywords: | Acute coronary syndroms Anticoagulantion Antiplatelet Percutaneous coronary intervention Risk stratification |
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