VCE取材Bethesda 2001报告在宫颈癌筛查中的意义

目的：探讨VCE取材Bethesda 2001报告系统在宫颈癌筛查中的意义。方法：采用VCE取材Bethesda2001报告系统对3 056例健康体检女性进行阴道细胞学检查，并对不明确意义的不典型鳞状上皮细胞（ASC-US）以上病变者经阴道镜取材进行宫颈组织病理学诊断。结果：阴道细胞学检查(VCE取材Bethesda 2001报告系统)检出宫颈异常鳞状上皮细胞66例，阳性率2.15%。其中不明确意义的不典型鳞状上皮细胞（ASC-US）17例（25.76％），不除外高度病变的不典型鳞状上皮细胞（ASC-H）4例，（6.06％），低度鳞状上皮内病变（LSIL）28例（42.42％），高度鳞状上皮内病变(HSIL)14例（21.21％），宫颈鳞癌（SCC）3例（4.55％）。66例细胞学阳性诊断病例经宫颈活检组织病理学诊断CIN I级以上病变60例（90.91％），其中CIN Ⅰ级35例（53.03％），CIN Ⅱ级12例（18.18％），CIN Ⅲ级7例（10.61％），宫颈鳞癌6例（9.09％）。结论：VCE取材Bethesda2001报告系统取材方便、报告准确，阴道细胞学检查阳性诊断与病理诊断符合率高达90.91％，VCE取材Bethesda2001报告系统在宫颈癌筛查中具有重要意义。

Significance of VCE smear and Bethesda 2001 report system in screening of cervical carcinoma

Objective To discuss the significance of VCE smear and the Bethesda 2001 report system in screening of cervical carcinoma. Methods 3 056 healthy examination population were examined for cervical-vaginal cytology by VCE smear and the Bethesda 2001 report system. All of the cases were biopsied by coloscopy including atypical squamous cells of undetermined significance(ASC-US), squamous intraepithelial lesions and carcinoma(SIL+). Results 66 cases of SIL+ were found in cervical-vaginal cytology (2.15%), including 17 cases of atypical squamous cells with undetermined significance(ASC-US) (25.76%), 4 cases of atypical squamous cells, didn't exclude HSIL(ASC-H)(6.06%), 28 cases of low-grade SIL(LSIL)(42.42%), 14 cases of high-grade SIL(HSIL)(21.21%), 3 cases of squamous cervical carcinoma(SCC)(4.55%). In 66 cases of cervical-vaginal cytology positive results, 60 cases of CIN I+ were confirmed by biopsy pathology, including 35 cases of CIN Ⅰ(53.03%), 12 cases of CIN Ⅱ(18.18%), 7 cases of CIN Ⅲ(10.61%). Conclusion VCE smear and the Bethesda 2001 report system can get cells conveniently and the results are more correct.The coincidence of the examination of cervical-vaginal cytology and pathology is 90.91%. VCE smear and the Bethesda 2001 report system has great significance in screening of cervical carcinoma.