| 慢性乙型肝炎肝组织的超微结构观察 |
| |
| 引用本文： | 王远萍,邱德贵,孙维纲,廖骏.慢性乙型肝炎肝组织的超微结构观察[J].四川大学学报(医学版),1987(3). |
| |
| 作者姓名： | 王远萍 邱德贵 孙维纲 廖骏 |
| |
| 作者单位： | 华西医大电子显微镜室
(王远萍)，华西医大传染内科学教研室
(邱德贵)，华西医大病理学教研室
(孙维纲)，华西医大电子显微镜室(廖骏) |
| |
| 摘 要： | 作者对41例慢性乙肝作了电镜观察,结果发现慢活肝时,淋巴细胞明显浸润并损伤肝细胞,提示慢活肝淋巴细胞的免疫功能可能比慢迁肝强。此外,根据超微结构特点作者提出了肝微循环的改变以及肝细胞内滑面内质网的增生程度可作为电镜下慢活肝和慢迁肝的区别点。
|
| 关 键 词： | 慢性活动性乙型肝炎 慢性迁延性乙型肝炎 超微结构 肝组织 |
ULTRASTRUCTURAL OBSERVATION OF HEPATIC TISSUE WITH CHRONIC HEPATITIS B |
| |
| Wang Yuanping,Qiu Degui,Sun Weigang,Liao Jun Electron Microscope Laboratory.ULTRASTRUCTURAL OBSERVATION OF HEPATIC TISSUE WITH CHRONIC HEPATITIS B[J].Journal of West China University of Medical Sciences,1987(3). |
| |
| Authors: | Wang Yuanping Qiu Degui Sun Weigang Liao Jun Electron Microscope Laboratory |
| |
| Institution: | Wang Yuanping;Qiu Degui;Sun Weigang;Liao Jun Electron Microscope Laboratory Department of Medicine of Infectious Diseases Department of Pathology |
| |
| Abstract: | Liver biopsy specimens from fourty-onepatients with chronic hepatitis B wereobserved under the electron microscope.Allof them were positive for hepatitis B sur-face antigen in RPHA system. Histological-ly, thirty-one had chronic active hepatitisB(CAH): 10 cases mild; 11 cases moderateand 10 cases severe. Ten had chronic per-sistent hepatitis B (CPH). The interrelationship between the infil-tration of lymphocytes and injury of hepa-tocytes was examined. The number of lym-phocyte infiltrated into hepatocytes in CAHwere much more than those in CPH. Thedegree of hepatocytic injury in CAH wasmuch more severe than that in CPH. Thisobservation confirms that cell mediate im-munity plays an important role in thepathogenesis of CAH. The observations also showed that therewere basic membranelike substances on thesurface of hepatocytes and also on the wallof hepatic sinusoid in CAH. It is suggestedthat these two ultrastructural changes mayserve as one of the differential diagnosticcriteria between CAH and CPH. |
| |
| Keywords: | Chronic active hepatitis B Chronic persistent hepatitis B Ultrastructure Hepatic tissue |
| 本文献已被 CNKI 等数据库收录！ |
