米非司酮配伍桂枝茯苓胶囊对子宫肌瘤患者血清性激素水平的影响

目的观察米非司酮配伍桂枝茯苓胶囊对子宫肌瘤患者血清性激素水平的影响及临床效果。方法将62例确诊为子宫肌瘤的患者进行药物治疗,将其随机分为两组:观察组口服米非司酮10mg,1次/d,共3个月,3个月后加服桂枝茯苓胶囊,3片/次,3次/d,共服3个月;对照组单独口服米非司酮10mg,1次/d,共服3个月。结果两组服用米非司酮期间均闭经,血红蛋白上升,子宫肌瘤平均体积均明显缩小,血清性激素水平明显下降,观察组远期复发率较对照组明显降低,两组间差异有显著性(P<0.05)。结论米非司酮配伍桂枝茯苓胶囊是目前中西医结合保守治疗子宫肌瘤的一种经济实用方法。

Clinical Study of Uteromyoma Treated with Mifepristone and Cassia Tuckahoe Capsule

Objective To observe the clinical effect of uteromyoma treated with mifepristone coordinated cassia tuckahoe capsule. Methods 62 patients of uteromyoma were randomly divided into two groups. Observation group was given mifepristone orally in a dose of 10 mg one daily for three months. After three months, cassia tuckahoe capsule was added with a dose of 3 capsules three daily for three months. Control group was given mifepristone orally with a dose of 10 mg one dailly for three months. Results Hemoglobin was increased, while mean volume of uteromyoma was reduced, and levels of serum sex hormone were clearly reduced. Amenorrhoea was appeared in two groups. Recurrence rate of uteromyoma were greatly reduced in observation group compared with control group (P <0.05). Conclusion Combination of mifepristone with cassia tuckahoe capsule was effective on conservative treatment of uteromyoma in combined treatment of traditional Chinese medicine and western medicine.