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SPECT,CT and MRI in a Turkish family with huntington's disease
Authors:R. P. M. Bruyn  G. Hageman  J. A. G. Geelen  F. A. van der Weel  A. R. Rozeboom  F. Barkhof  P. Scheltens
Affiliation:(1) Department of Neurology, Medisch Spectrum Twente, Enschede, The Netherlands;(2) Department of Nuclear Medicine, Medisch Spectrum Twente, Enschede, The Netherlands;(3) Department of Diagnostic Radiology, Medisch Spectrum Twente, Enschede, The Netherlands;(4) Department of Diagnostic Radiology, Free University Hospital, Amsterdam, The Netherlands;(5) Department of Neurology, Free University Hospital, Amsterdam, The Netherlands;(6) Department of Neurology, Oudenrijn Hospital Utrecht, van Heuven Goedhartlaan 1, NL-3527 CE Utrecht, The Netherlands
Abstract:A Turkish family with Huntington's disease documented on CT, MRI and SPECT is reported. Whereas in clinically definite cases CT and MRI are of limited value and SPECT does not add anything of value, in one asymptomatic subject SPECT showed moderate caudate nucleus hypoperfusion, underlining the hypothesis that SPECT may have a role in predicting Huntington's disease.
Keywords:Huntington's disease  Computed tomography  Magnetic resonance imaging  Single photon emission computed tomography
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