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艾司西酞普兰治疗抑郁症对照研究
引用本文:张富,毛庆娟,施万平,张志荣,张华彪.艾司西酞普兰治疗抑郁症对照研究[J].临床精神医学杂志,2008,18(1):49-50.
作者姓名:张富  毛庆娟  施万平  张志荣  张华彪
作者单位:河北张家口市沙岭子医院,075131
摘    要:目的:探讨艾司西酞普兰治疗抑郁症的疗效及安全性。方法:将63名抑郁症患者随机分为两组,分别给予艾司西酞普兰和马普替林治疗,疗程6周。采用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表病情严重程度(CGI—SI)、治疗中出现的症状量表(TESS)评定疗效及不良反应。结果:艾司西酞普兰与马普替林治疗抑郁症疗效相当,但艾司西酞普兰起效更快,不良反应更少。结论:艾司西酞普兰治疗抑郁症安全有效。

关 键 词:艾司西酞普兰  抑郁症
文章编号:1005-3220(2008)01-0049-02
收稿时间:2007-06-01
修稿时间:2007年6月1日

Control study of escitalopram and maprotiline in treatment of depression
ZHANG Fu,MAO Qing-juan,SHI Wan-ping,ZHANG Zhi-rong,ZHANG Hua-biao.Control study of escitalopram and maprotiline in treatment of depression[J].Journal of Clinical Psychological Medicine,2008,18(1):49-50.
Authors:ZHANG Fu  MAO Qing-juan  SHI Wan-ping  ZHANG Zhi-rong  ZHANG Hua-biao
Institution:ZHANG Fu, MAO Qing-juan, SHI Wan-ping, ZHANG Zhi- rong , ZHANG Hua- biao (Shalingzi Hospital of Zhangjiakou City, Zhangjiakou 075131, China)
Abstract:Objective:To detect the efficacy and side effects of escitalopram in the treatment of depresssion.Method:63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks.Hamilton depressive scale(HAMD),clinical global impression severity of illness(CGI-SI)and treatment emergant symptom scale(TESS)were used to evaluate the efficacy and side effects before and after the treatment.Results:There was no significant difference in the efficacy between these two groups.Escitalopram took effect more quickly and less side effects than maprotiline.Conclusion:Escitalopram is a safe and effective antidepressant.
Keywords:escitalopram  depression
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