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Th2细胞因子与支气管哮喘发病机制的研究进展
引用本文:胡娜,王红.Th2细胞因子与支气管哮喘发病机制的研究进展[J].国际呼吸杂志,2008,28(19):1185-1187.
作者姓名:胡娜  王红
作者单位:辽宁医学院附属第一医院呼吸内科,锦州,121001
摘    要:支气管哮喘(简称哮喘)是由多种细胞和细胞因子参与的肺部慢性炎症性疾病.发病机制尚未完全清楚.目前认为Th1/Th2反应失衡导致Th2细胞过度激活是其重要的免疫学机制之一.Th2细胞产生的多效性细胞因子白介素4(IL-4)、IL-5和IL-13在此过程中发挥巨大作用,与哮喘发病密切相关.

关 键 词:Th2细胞因子  支气管哮喘  发病机制  进展

Progress of Th2 cytokines and bronchial asthma pathogenesis
HU Na,WANG Hong.Progress of Th2 cytokines and bronchial asthma pathogenesis[J].International Journal of Respiration,2008,28(19):1185-1187.
Authors:HU Na  WANG Hong
Abstract:Bronchial asthma(asthma) is a chronic inflammatory disease of the lung,which is involvedwith various cells and cytokines. The pathogenesis of asthma is not well-known yet. Now it is recognized thatthe imbalance of Th1/Th2 response leading to excessive activation of the Th2 cells is one of the importantmechanisms of immunology. The polyphenic cytokines produced by Th2 cells,such as IL-4,IL-5 and IL-13,have been certified to play a significant role in this process and are related with asthma pathogenesis.
Keywords:Th2 cytokines  Bronchial asthma  Pathogenesis  Progress
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