| ^18F—FLT对恶性肿瘤治疗效果的评估价值 |
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| 引用本文： | 李红梅,冯珏,李晓东,张建阳. ^18F—FLT对恶性肿瘤治疗效果的评估价值[J]. 国外医学(放射医学核医学分册), 2009, 0(3): 136-139 |
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| 作者姓名： | 李红梅 冯珏 李晓东 张建阳 |
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| 作者单位： | 河北医科大学第二医院核医学科,石家庄050000 |
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| 摘 要： | 形态影像学作为评价恶性肿瘤治疗效果的传统方法，因所需时间较长，不能从生物学角度进行评价，逐渐被分子影像学方法所取代。^18F-氟脱氧葡萄糖（^18F—FDG）PET虽然在多种肿瘤的诊断、分期及疗效监测中显示了突出的优势，但由于特异性较差，不能对恶性肿瘤的治疗效果进行准确评价。研究表明，^18F-氟胸苷（^18F-FLT）PET最大的应用前景在于监测肿瘤的治疗效果，且优于^18F—FDG。
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| 关 键 词： | 肿瘤 氟脱氧葡萄糖F18 氟脱氧胸苷F18 |
The value of ^18F-fluorothymidine to monitor the therapeutic effect of malignant tumor |
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| LI Hong-mei,FENG Jue,LI Xiao-dong,ZHANG Jian-yang. The value of ^18F-fluorothymidine to monitor the therapeutic effect of malignant tumor[J]. Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine), 2009, 0(3): 136-139 |
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| Authors: | LI Hong-mei FENG Jue LI Xiao-dong ZHANG Jian-yang |
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| Affiliation: | ( Department of Nuclear Medicine, the 2nd Hospital of Hebei Medical University, Shijiazhuang 050000, China ) |
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| Abstract: | Morphology imaging as a traditional method to evaluate the therapeutic effect of malignant tumor, needs to much time and can＇ t reflect the biological changes. So it is replaced by molecular imaging method gradually. ^18F-fluorodeoxyglucose （^18F-FDG） PET imaging shows remarkable merit in the diagnosis, staging diagnosis and effcet monitoring of many kinds of tumor, but its specificity is low. So it can＇ t evaluate the therapeutic effect accurately. Studies show that the prospect of ^18F-fluorothymidine PET imaging is to monitor the therapeutic effect of malignant tumor, and is better than that of ^18F-FDG. |
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| Keywords: | Neoplasms Fluorodeoxyglucose F18 Fluorothymidine F18 |
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