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Pericyte endothelial gap junctions in human cerebral capillaries |
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| Authors: | P Cuevas J A Gutierrez-Diaz D Reimers M Dujovny F G Diaz J I Ausman |
| Affiliation: | (1) Department of Research (Histology), Centro Ramón y Cajal, Ctra. de Colmenar, km.9.100, 34 Madrid, Spain;(2) Department of Neurosurgery, Centro Ramón y Cajal, Ctra. de Colmenar, km.9.100, 34 Madrid, Spain;(3) Department of Surgical Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, 48202 Detroit, MI, USA;(4) Servicio de Histologia, Dpto. de Investigación, Centro Ramón y Cajal, Ctra. de Colmenar, Km.9.100, 34 Madrid, Spain |
| Abstract: | Summary Human cerebral tissue has been ultrastructurally studied and gap junctions have been visualized between endothelial cells and pericytes that permit ion exchange. We propose that the functional interrelationship between endothelium and pericytes may play a role in the alteration of capillary diameter for the control of local cerebral blood flow. |
| Keywords: | Human cerebral capillaries Pericytes Endothelium Gap junctions |
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