| 加味硝石矾石散对免疫性肝损伤影响的实验研究 |
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| 引用本文： | 王付,沈芸,曹震. 加味硝石矾石散对免疫性肝损伤影响的实验研究[J]. 北京中医药大学学报, 2000, 23(5): 39-41 |
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| 作者姓名： | 王付 沈芸 曹震 |
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| 作者单位： | 1. 河南中医学院 河南 450003
2. 河南省济源克井医院 河南 454661 |
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| 基金项目： | 河南省教育厅科技攻关项目;; |
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| 摘 要： | 实验诱导小鼠免疫肝损伤模型，检测其丙氨酸氨基转移酶(ALT)和天门冬氨酸氨基转移酶(AST)活性增高。加味硝石矾石散能明显降低小鼠血清ALT、AST活性，并在其作用效果上存在一定的量效关系；并能抑制细胞因子(IL-6、TNF-α)的水平升高，且其效果与药量呈正相关关系。
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| 关 键 词： | 免疫性肝损伤 加味硝石矾石散 肝功能 细胞因子 Immune Hepatic Injury Fortified Xiaoshifanshi Powder Liver Function |
| 修稿时间： | 1999-05-19 |
Experimental Study on the Effects of Fortified Xiaoshifanshi Powder on Hepatic Immune Injury |
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| Wang Fu,Shen Yun,Cao Zhen. Experimental Study on the Effects of Fortified Xiaoshifanshi Powder on Hepatic Immune Injury[J]. Journal of Beijing University of Traditional Chinese Medicine, 2000, 23(5): 39-41 |
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| Authors: | Wang Fu Shen Yun Cao Zhen |
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| Abstract: | A TCM preparation named Fortified Xiaoshifanshi Powder was given to the mouse model of immune hepatic injury, and the results showed that the preparation could obviously decrease the serum ALT and AST activity in the animals of the model group in a certain dose-effect manner, and inhibit the increase of IL-6 and TNF-α levels with a positive correlation between the effect and the size of the dose. |
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| Keywords: | Immune Hepatic Injury Fortified Xiaoshifanshi Powder Liver Function IL-6 TNF-α |
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