Potential clindamycin resistance in clindamycin-susceptible, erythromycin-resistant Staphylococcus aureus: report of a clinical failure |
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Authors: | Levin Todd P Suh Byungse Axelrod Peter Truant Allan L Fekete Thomas |
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Affiliation: | Temple University Hospital, Section of Infectious Diseases, 3401 North Broad St., Philadelphia, PA 19140, USA. TLevin9696@yahoo.com |
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Abstract: | The erm gene product confers clindamycin resistance on Staphylococcus aureus. We report a clindamycin clinical failure where resistance developed on therapy in a D-test-positive strain. D tests of 91 clindamycin-susceptible, erythromycin-resistant S. aureus isolates showed that 68% of methicillin-susceptible and 12.3% of methicillin-resistant S. aureus strains were D-test positive. |
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