专题关于现行《国标》两个问题的思考

大群饲养的实验用猴,B病毒抗体阳性率高达60%~70%。现行《实验动物国家标准》规定,B病毒为普通级实验猴必检项目,并且要求"被测猴血清中的BV抗体"为阴性。作为国家标准,如果脱离了该国行业的实情,那就要权衡修订。实验动物饲料硬度/松脆度没能作为一个指标被列入《国标》,而这个指标可以大大影响了实验动物饲料的摄入和受试动物的生理状况。建议将该指标吸纳进《国标》,进行通盘考量。

Two considerations about the current National Standard of Laboratory Animals

According the current National standard for laboratory animal, herpes B virus antibody must be tested and negative for all the breed/tested macaques,howere,in fact the positive rate is around 60-70% in breeding colony. Being the National Standard, if it is too far from the reality of the filed, weighing and changing should be made. Hardness/crispness degree of laboratory animal diet never been considered as a listed value in the National Standard for Laboratory Animal to identify the quality of diet. In fact, this index affects a lot about daily diet intake and physiological status of laboratory animals. Hereby, the authors suggest to take the index into the National Standard, to assess the quality of laboratory animal diet in a more comprehensive way.