| 己酮可可碱在脓毒症中的作用和机制 |
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| 引用本文： | 王莉琴,徐建国. 己酮可可碱在脓毒症中的作用和机制[J]. 医学研究生学报, 2004, 17(7): 661-663 |
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| 作者姓名： | 王莉琴 徐建国 |
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| 作者单位： | 南京军区南京总医院麻醉科,江苏南京,210002 |
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| 摘 要： | 脓毒症可促使宿主发生复杂炎症的病理生理改变。己酮可可碱(Pentoxifylline，PTX)是甲基黄嘌呤的衍生物，具有选择性抗炎作用。作者阐述了PTX在脓毒症中作用和机制的实验研究和临床试验，为脓毒症的治疗提供新的思路。
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| 关 键 词： | 己酮可可碱 脓毒症 抗炎作用 |
| 文章编号： | 1008-8199(2004)07-0661-03 |
| 修稿时间： | 2003-04-25 |
Effects and mechanisms of pentoxifylline in sepsis |
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| WANG Li qin reviewing,XU Jian guo checking. Effects and mechanisms of pentoxifylline in sepsis[J]. Bulletin of Medical Postgraduate, 2004, 17(7): 661-663 |
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| Authors: | WANG Li qin reviewing XU Jian guo checking |
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| Abstract: | It is increasingly evident that sepsis triggers a complex host reaction, which is responsible for a variety of pathophysiologic changes during the inflammatory process. Pentoxifylline (PTX) is a methyxanthine with selective anti inflammatory activity. The effects and mechanisms of PTX in human and animal models of sepsis are reviewed, for providing new information in treatment of sepsis. |
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| Keywords: | Pentoxifylline Sepsis Anti imflammatory |
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