| 抑癌基因与胃癌早期诊断 |
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| 引用本文： | 杜金荣,宋茂力,傅红,徐筠如. 抑癌基因与胃癌早期诊断[J]. 临床肿瘤学杂志, 1998, 3(4): 1-3 |
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| 作者姓名： | 杜金荣 宋茂力 傅红 徐筠如 |
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| 作者单位： | 哈尔滨医科大学附属第二医院 |
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| 摘 要： | 目的:研究71例正常胃粘膜,胃粘膜炎症伴中、重度不典型增生、早期胃癌和进展期胃癌标本,了解肿瘤抑癌基因与胃癌的关系.方法:用免疫组化方法观察p21、p53和p16蛋白表达.结果:p21与p53的上调性阳性表达与不典型增生的程度有关,而P16呈下调性表达改变.结论:p21、p53及p16的表达异常与胃癌发生有关.检测这些指标可作为胃癌癌前病变的显著性标志.
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| 关 键 词： | 胃肿瘤 癌前病变 抑癌基因 免疫组织化学 |
The relationship between tumor suppressor gene and early diagnosis of gastric carcinoma |
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| Du Jinrong,Song Maoli,Fu Hong,et al.. The relationship between tumor suppressor gene and early diagnosis of gastric carcinoma[J]. Chinese Clinical Oncology, 1998, 3(4): 1-3 |
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| Authors: | Du Jinrong Song Maoli Fu Hong et al. |
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| Affiliation: | Du Jinrong,Song Maoli,Fu Hong,et al. The second Affiliated Hospital of Haerbin Medical University,Haerbin 150086 |
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| Abstract: | |
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| Keywords: | Stomach neoplasms Precancerous process Tumor suppressor gene Immunohistochemisty |
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