| 肿瘤M2型丙酮酸激酶检测在结肠癌诊断中的临床价值 |
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| 引用本文： | 张丹. 肿瘤M2型丙酮酸激酶检测在结肠癌诊断中的临床价值[J]. 中国卫生标准管理, 2021, 0(6): 95-98 |
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| 作者姓名： | 张丹 |
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| 作者单位： | 吉林医药学院附属医院消化内科 |
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| 基金项目： | 吉林市医疗卫生指导性计划项目(201830589)。 |
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| 摘 要： | 目的 探究肿瘤M2型丙酮酸激酶检测在结肠癌诊断中的临床价值.方法 选取本院经病理诊断确诊为结肠癌的50例患者与结肠腺瘤的60例患者分别设为结肠癌组与结肠腺瘤组,选择90例健康人设为正常组,分别使用ELISA、化学发光法(CL)检测血浆M2-PK数值及癌胚抗原(CEA)水平.结果 结肠癌组及Dukes C、D期肿瘤M2-...
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| 关 键 词： | 肿瘤M2型丙酮酸激酶 结肠癌 M2-PK 癌胚抗原 特异性 诊断价值 |
The Clinical Value of Tumor M2 Pyruvate Kinase Detection in the Diagnosis of Colon Cancer |
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| ZHANG Dan. The Clinical Value of Tumor M2 Pyruvate Kinase Detection in the Diagnosis of Colon Cancer[J]. China Health Standard Management, 2021, 0(6): 95-98 |
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| Authors: | ZHANG Dan |
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| Affiliation: | (Department of Gastroenterology,Affiliated Hospital ofJilin Medical College,Jilin Jilin 132011,China) |
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| Abstract: | Objective to explore the clinical value of tumor M2 pyruvate kinase in the diagnosis of colon cancer.Methods 50 patients with colon cancer and 60 patients with colon adenoma diagnosed by pathology in our hospital were selected as colon cancer group and colon adenoma group respectively,and 90 healthy people were selected as normal group.The plasma M2-PK value and carcinoembryonic antigen(CEA)level were detected by ELISA and chemiluminescence(CL).Results The level of M2-PK in colon cancer group and Dukes stage C and D was significantly higher than that in colon adenoma group,normal group and Dukes stage A and B(P<0.05).The sensitivity of M2-PK in colon cancer was significantly higher than that in CEA.Conclusion The detection of tumor M2 pyruvate kinase has high clinical value in the diagnosis of colon cancer,and the sensitivity of tumor M2-PK is higher than CEA,which has a very close relationship with tumor stage,and can be effectively applied in the screening and diagnosis of colon cancer. |
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| Keywords: | tumor M2 pyruvate kinase colon cancer M2-PK carcinoembryonic antigen specificity diagnostic value |
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