早期肠内营养支持对重度慢性阻塞性肺疾病急性加重期治疗后呼吸功能及营养状态改善的影响

目的 探讨在重度慢性阻塞性肺疾病(COPD)急性加重期治疗中采用早期肠内营(EN)养支持的效果.方法 收集朝阳市第四医院2017年1月—2019年12月收治的重度COPD急性加重期患者90例,随机分为对照组和观察组各45例.对照组采用肠外营养(PN)续贯EN模式;观察组采用早期持续EN模式,比较两组患者的呼吸功能、血离...

Effect of Early Enteral Nutrition Support on Respiratory Function and N utritional Status in Patients with Acute Exacerbation of Severe Chronic Obstructive Pulmonary Disease

Objective To investigate the effect of early enteral nutrition(EN)support in the treatm ent of acute exacerbation of severe chronic obstructive pulmonary disease(COPD).Methods A total of 90 patients with acute exacerbation of severe COPD in our hospital from January 2017 to December 2019 were collected and randomly divided into control group and observation group,with 45 cases in each group.The control group was given parenteral nutrition(PN)continuous EN mode,and the observation group was given early continuous EN mode.The respiratory function,blood ion and vitamin levels of the two groups were compared.Results There were significant differences in pH,PaO₂,PaCO₂,SaO,FVC,FEV₁and FEV₁/FVC between the two groups(P<0.05).The differences of K,Na,Cl,CA,P and Mg in peripheral blood between the two groups were significant(P<0.05).Moreover,the differences of VitA,VitB,VitC,VitD and VitE were also significant(P<0.05).Conclusion Early application of EN in the treatment of acute exacerbation of severe COPD can effectively improve the nutritional status of patients and promote the recovery of respiratory function,which is worthy of clinical application.