Recurrent sickle cell nephropathy in a transplanted kidney |
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Authors: | D J Miner D K Jorkasky L J Perloff R A Grossman J E Tomaszewski |
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Institution: | Department of Medicine, University of Pennsylvania, Philadelphia 19104. |
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Abstract: | Of patients who developed end-stage renal disease secondary to sickle cell anemia (SCA), some have undergone renal transplantation with reasonable success. We recently cared for a patient with SCA and a functioning, transplanted kidney who experienced a permanent decline in renal function three and one-half years following transplant. The evaluation of his renal dysfunction revealed multiple features to support recurrence of sickle cell nephropathy as the cause for the deterioration. |
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