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Subtypes of B44 in six different populations. |
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| Authors: | Ann McNicholas Yao Z M Hammond E Dondi MC Cuccia A Bartova J Drabek D Chandanayingyong ED Albert |
| Institution: | 4 Immunogenetics Laboratory, University of München, D Italia 2 Natal Institute of Immunology Durban SA Italia 3 Istituto di Genetica, Università di Pavia Italia a HLA-Lab., Childrens Hospital, University of Olomouc, CR Bangkok Thailand b Siriraj Hospital, Mahidol University Bangkok Thailand |
| Abstract: | We have investigated the distribution of HLA-B44 subtypes in various populations, see table. Of the five B44 subtypes investigated, two are apparently quite rare because they were only found in the local central european panel (B*4404 and B*4406). The european populations are characterized by a relatively high frequency of B*4402, while in the Albanian, in the Asiatic and African populations, the subtype B*4403 is prevailing. The distribution of the B44 subtypes in the Czech and the Munich population are virtually the same. We conclude from these data, that B44 subtypes have different distributions in different populations of the world and must therefore be taken into consideration when matching for bone marrow transplantation. |
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