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Blood lead and efythrocyte protoporphyrin levels in Kazakhstan
Authors:Balkrishena Kaul  James Rasmuson  Roger L Olsen  Curt R Chanda  Tatiana I Slazhneva  Eduard I Granovsky  Andrey A Korchevsky
Institution:(1) Kaulson Laboratories, Inc., 691 Bloomfield Avenue, 07006 West Caldwell, NJ, USA;(2) Share International Inc., Wheat Ridge, CO, USA;(3) The Centre for Health Care and Ecological Protection, Almaty, Kazakhstan
Abstract:A pilot study was conducted to examine the extent of lead exposure and prevalence of iron deficiency in 3 major cities of Kazakhstan. Blood lead (B-Pb.) and erythrocyte protoporphyrin (ZnPP) levels of 475 children, age range 6 months to 7 yeas were measured. The mean B-Pb. levels in the different cities ranged from 4–7 ug/dl (minimum 1 to max 29 ug/dl) and similarly the mean ZnPP levels ranged from 26–32 ug/dl (minimum 12 and maximum 95 ug/dl), thus confirming low level lead poisoning of children at some sites. One to four year olds had greater than 10 ng/dl B-Pb in 18–27% cases compared with 3–7% cases in five to seven year olds. Prevalence of iron deficiency in 6 months to 4 year old children was the highest ranging from 28–86% compared with 4 to 15% in 4–7 year olds. However, there was remarkably low prevalence (4%) of iron deficiency in a group of 5–6 years olds. This study suggests that a targeted B-Pb and ZnPP monitoring together with an iron supplementation programme in the 3 cities of Kazakhstan is essential. Environmental education appears to have had a positive impact in lowering B-Pb at one site and should thus be expanded nationwide.
Keywords:Blood lead  Erythrocyte protoporphyrin
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