|
|||||
|
|
| 小鼠感染旋毛虫后血清抗体水平的变化 | |
| 引用本文： | 李婷婷,马素好,崔晶,王中全.小鼠感染旋毛虫后血清抗体水平的变化[J].中国热带医学,2009,9(3):421-422. |
| 作者姓名： | 李婷婷 马素好 崔晶 王中全 |
| 作者单位： | 1. 郑州大学医学院寄生虫学教研室,河南,郑州,450052;郑州澍青医学高等专科学校,河南,郑州,450064 2. 郑州澍青医学高等专科学校,河南,郑州,450064 3. 郑州大学医学院寄生虫学教研室,河南,郑州,450052 |
| 基金项目： | 河南省重大公益性科研招标项目(2008) |
| 摘 要： | 目的观察小鼠感染旋毛虫后血清抗体水平的变化。方法12只昆明小鼠每只经口感染旋毛虫肌幼虫300条，感染后11-28d每天尾静脉采血，分离血清，应用旋毛虫肌幼虫ES抗原ELISA检测血清抗体水平。结果小鼠感染旋毛虫后11d血清抗体阳性率为8．33％（1／12），感染后14d、20d的抗体阳性率分别升至16．67％（2／12）与58．33％（7／12）。感染后24d抗体阳性率达100％（12／12）并持续至实验结束时的28d。小鼠感染旋毛虫后的血清抗体阳性率与感染后时间有显著的相关性（r=0．984，P〈0．05）；血清抗体水平随感染后时间的延长而升高（F=177．427，P〈0．05）。结论小鼠感染旋毛虫后血清抗体水平随感染后时间的延长而升高，感染小鼠全部检出抗旋毛虫抗体的时间为感染后24d。 |
| 关 键 词： | 旋毛虫 抗旋毛虫体 ELISA 排泄-分泌抗原 小鼠 |
Observation on serum antibody levels in the mice experimentally infected with Trichinella spiralis |
|
| LI Ting-ting,MA Su-Hao,CUI Jing,et al..Observation on serum antibody levels in the mice experimentally infected with Trichinella spiralis[J].China Tropical Medicine,2009,9(3):421-422. | |
| Authors: | LI Ting-ting MA Su-Hao CUI Jing |
| Institution: | Department of Parasitology;Zhengzhou University Medical College;Zhengzhou 450052;Henan;P. R.China |
| Abstract: | Objective To observe the changes of serum antibody levels in the mice experimentally infected with Trichinella spiralis. Methods Each of 12 male Kunming mice was orally infected with 300 muscle larvae of T. spiralis, Blood was daily collected from the mice tail veins from 11th to 28th day post-infection (dpi) and serum was separated. the serum anti-Trichinella antibodies were detected by ELISA using excretory-secretory (ES) antigen of T. spiralis muscle larvae. Results The serum antibody positive rate of th... |
| Keywords: | EUSA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |