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Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment
引用本文:Min-zhi GAO Xiao-ming ZHAO Wen-ying LI Gui-mei LIU Xiao-feng JIA Hui-qin ZHANG. Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment[J]. 生殖与避孕(英文版), 2007, 18(3): 205-212. DOI: 10.1016/S1001-7844(07)60025-X
作者姓名:Min-zhi GAO Xiao-ming ZHAO Wen-ying LI Gui-mei LIU Xiao-feng JIA Hui-qin ZHANG
作者单位:Min-zhi GAO1,Xiao-ming ZHAO1,Wen-ying LI2,Gui-mei LIU2,Xiao-feng JIA2,Hui-qin ZHANG2 1. Reproductive Medicine Center of Renji Hospital,Medical College of Jiao Tong University,Shanghai 200001,China 2. Shanghai Institution of Planned Parenthood Research,Shanghai 200032,China
摘    要:Objective To evaluate endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound as a predicator of endometrial receptivity in women undergoing IVF treatment. Methods A total of 119 infertile patients undergoing the first IVF/ICSI-ET cycle were recruited. Three groups were divided according to a color Doppler ultrasound exami- nation performed on the day of hCG injection. Group A, endometrial and subendometrial blood flows were 2 branches and below; group B, endometrial and subendometrial blood flows were between 3 and 4 branches; group C, endometrial and subendometrial blood flows were 5 branches and above. Patients were transferred 1-3 embryos each. Demographic data, ovarian responses, endometrial thickness, PI, RI, development of embryo and IVF result among groups were compared. Results Demographic data, ovarian responses, endometrial thickness, PI, RI and development of embryo among groups have no significant difference. The pregnancy rate of group A was significantly lower than that of group B (P<0.05) and group C (P<0.01). The implantation rate of group A was significantly lower than than of group C (P<0.01). There was no significant difference of the rate of pregnancy and implantation between group B and group C (P>0.05). Conclusion Endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound is a good predicator of pregnancy during IVF treatment. A good endometrial and subendometrial blood flows is benefit for the result of IVF.

关 键 词:子宫内膜 血液流程 感受性 受精卵 彩色多普勒超声检查
收稿时间:2006-11-11
修稿时间:2006-11-11

Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment
Min-zhi GAO,Xiao-ming ZHAO,Wen-ying LI,Gui-mei LIU,Xiao-feng JIA,Hui-qin ZHANG. Assessment of Uterine Receptivity by Endometrial and Subendometrial Blood Flows Measured by Vaginal Color Doppler Ultrasound in Women Undergoing IVF Treatment[J]. Journal of Reproduction and Contraception, 2007, 18(3): 205-212. DOI: 10.1016/S1001-7844(07)60025-X
Authors:Min-zhi GAO  Xiao-ming ZHAO  Wen-ying LI  Gui-mei LIU  Xiao-feng JIA  Hui-qin ZHANG
Affiliation:Min-zhi GAO(Reproductive Medicine Center of Renji Hospital,Medical College of Jiao Tong University,Shanghai 200001,China);Xiao-ming ZHAO(Reproductive Medicine Center of Renji Hospital,Medical College of Jiao Tong University,Shanghai 200001,China);Wen-ying LI(Shanghai Institution of Planned Parenthood Research,Shanghai 200032,China);Gui-mei LIU(Shanghai Institution of Planned Parenthood Research,Shanghai 200032,China);Xiao-feng JIA(Shanghai Institution of Planned Parenthood Research,Shanghai 200032,China);Hui-qin ZHANG(Shanghai Institution of Planned Parenthood Research,Shanghai 200032,China);
Abstract:Objective To evaluate endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound as a predicator of endometrial receptivity in women undergoing IVF treatment. Methods A total of 119 infertile patients undergoing the first IVF/ICSI-ET cycle were recruited. Three groups were divided according to a color Doppler ultrasound exami- nation performed on the day of hCG injection. Group A, endometrial and subendometrial blood flows were 2 branches and below; group B, endometrial and subendometrial blood flows were between 3 and 4 branches; group C, endometrial and subendometrial blood flows were 5 branches and above. Patients were transferred 1-3 embryos each. Demographic data, ovarian responses, endometrial thickness, PI, RI, development of embryo and IVF result among groups were compared. Results Demographic data, ovarian responses, endometrial thickness, PI, RI and development of embryo among groups have no significant difference. The pregnancy rate of group A was significantly lower than that of group B (P<0.05) and group C (P<0.01). The implantation rate of group A was significantly lower than than of group C (P<0.01). There was no significant difference of the rate of pregnancy and implantation between group B and group C (P>0.05). Conclusion Endometrial and subendometrial blood flows measured by vaginal color Doppler ultrasound is a good predicator of pregnancy during IVF treatment. A good endometrial and subendometrial blood flows is benefit for the result of IVF.
Keywords:endometrial and subendometrial blood flows  endometrial receptivity  in vitro fertilization-embryo transfer(IVF)  color Doppler ultrasound
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