0.25%罗布卡因与0.25%布比卡因CEIA用于子宫切除术的对比研究

目的 :比较 0 .2 5 %罗布卡因与 0 .2 5 %布比卡因持续硬膜外输注 (CEIA)用于子宫切除术的镇痛效果。方法 :6 0例开腹子宫切除术的病例 ,随机分为A、B两组。A组用 0 .2 5 %罗布卡因 (n =30 ) ,B组用 0 .2 5 %布比卡因 (n =30 ) ,每组均加入芬太尼2 μg .ml-1。观察并记录镇痛效果、运动阻滞、镇痛剂的需要量、副作用等。结果 :①两组病人CEIA时VAS评分无显著性差异 ,术后 8h、2 4hBromage评分 >0者 ,A组低于B组 ,但无显著性差异。②胃肠功能重建的时间及PONV的发生率无显著性差异。③术后对哌替啶的需要量及例次无显著性差异。结论 :0 .2 5 %罗布卡因CEIA用于开腹子宫切除术后镇痛两者都好

Effect of continuous epidural infusion of 0.25% ropivacaine or 0.25% bu pivacaine on postoperative analgesia after abdominal hysterectomy

Objective:The purpose of this study was investigate the effect of postoperative continuos epidural infusion of 0.25% ropivacaine or 0.25% bupivacaine 4ml.h- 1on pain.Methods:60 cases with abdominal hysterectomy were divided into group A and B at random, and 0.25% ropivacaine was administered to group A(n=30), while 0.25% bupivacaine to group B(n=30) as well as fentanly 2ug.ml-1 for both to observe the analgesic effect, motor block, required analgesic dosage, side effect and so on.Results:There were no significant differences between two groups in VAS score,and the number of patients requesting supplementary pethidine, Bromage score and time to first flatus or stool. Conclusion:0.25% ropivacaine used in postoperative continuous epidural infusion analgesia is superior to 0.25% bupivacaine in patients undergoing hysterectomy.