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女性肥胖与E2、FSH、PRL、血脂及SOD关系的研究
引用本文:王立金,方玉荣. 女性肥胖与E2、FSH、PRL、血脂及SOD关系的研究[J]. 辽宁医学院学报, 2006, 27(3): 46-47
作者姓名:王立金  方玉荣
作者单位:安徽理工大学医学院,安徽,淮南,232001;安徽理工大学医学院,安徽,淮南,232001
摘    要:目的 观察中老年妇女肥胖与血清性激素、血脂、自由基的关系,探讨中老年妇女肥胖的可能机制.方法调查对象为35~62岁的妇女,按体重指数(BMI)分为4组:(1)肥胖组,BMI≥28,(2)超重组,24≤BMI<28,(3)正常组,18.5≤BMI<24,(4)消瘦组,分别测定血脂、血清中雌二醇(E2)、卵泡刺激素(FSH)、催乳素(PRL)和血清中SOD、MDA、NO含量.结果肥胖和超重者分别占被调查的10.0%和32.8%,肥胖组中血脂(除APOA1)、E2、SOD、MDA、NO与正常组比较,均有显著性差异(P<0.05).结论中老年妇女肥胖可引起血脂增高,雌激素水平下降,自由基增多.

关 键 词:肥胖  性激素  血脂  自由基  中老年妇女
文章编号:1000-5161(2006)03-0046-02
收稿时间:2006-01-15
修稿时间:2006-01-15

Relationship Between Estrogen, Lipoid, Free Radical in Serum and Obesity in Mid- elderly Women
WANG Li-jin,FANG Yu-rong. Relationship Between Estrogen, Lipoid, Free Radical in Serum and Obesity in Mid- elderly Women[J]. Journal of Liaoning Medical University (LNMU) Bimonthly, 2006, 27(3): 46-47
Authors:WANG Li-jin  FANG Yu-rong
Affiliation:Medical College of Anhui Science and Technology University, Huainan 232001 China
Abstract:Objective To observe the relationship between estrogen,lipoid,free radical in serum and obesity in mid-elderly women.Methods The mid-elderly women were divided into 4 groups in BMI.group 1,obesity,group 2,overweight,group 3,normal,group 4,lowweight.They were determined by the level of E_2,FSH,PRL,lipoid,SOD,MDA,NO in serum.ResultsThe rate of obesity and overweight is respectively 10.0%,32.8% in the mid-elderly women.There was significant difference of E_2,TC,TG,LDL-C,LDL,ApoB,ApoA_1/ ApoB,SOD,MDA in serum between obesity groups and normal groups((P<0.05).)Conclusions Obesity may induce rise of level of lipoid, decline of estrogen,increase of free radical.
Keywords:obesity   estrogen   serum lipoid   free redieal   mid -elderly women
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