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Ⅰ型胶原基因与近视关系的研究进展
引用本文:纪风涛,周翔天,瞿佳.Ⅰ型胶原基因与近视关系的研究进展[J].眼视光学杂志,2010,12(2):155-158.
作者姓名:纪风涛  周翔天  瞿佳
作者单位:温州医学院附属眼视光医院,浙江,温州,325027
摘    要:目前近视的发生率很高,但发病机制不清.实验性近视眼和人类近视眼研究发现,I型胶原基因变化与近视发生、发展关系密切,本文就Ⅰ型胶原基因的表达调控及其与近视的关系作一综述.

关 键 词:Ⅰ型胶原  COL1α1  基因  近视

Type I collagen and myopia
JI Feng-tao,ZHOU Xiang-tian,QU Jia.Type I collagen and myopia[J].Chinese Journal of Optometry & Ophthalmology,2010,12(2):155-158.
Authors:JI Feng-tao  ZHOU Xiang-tian  QU Jia
Institution:(Eye Hospital, Wenzhou Medical College, Wenzhou 325027, China)
Abstract:The prevalence of myopia is increasing in present, but the mechanism remains unclear. Studies in myopic sclera of animals and human showed collagen type I has closely related to the development of myopia. So in this paper we reviewed the expression and regulation of type I collagen gene, as well as the relationship between myopia and type I collagen gene.
Keywords:Collagen type I  Collagen type I  alpha 1  Gene  Myopia
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