| 唑吡坦治疗失眠症双盲研究 |
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| 引用本文： | 张宏根,赵靖平,陈远光,陈晋东,李文.唑吡坦治疗失眠症双盲研究[J].临床精神医学杂志,2001,11(3):146-147. |
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| 作者姓名： | 张宏根 赵靖平 陈远光 陈晋东 李文 |
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| 作者单位： | 1. 长沙,湖南省脑科医院
2. 湖南医科大学附二院精神卫生研究所 |
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| 摘 要： | 目的：比较国产唑吡坦片和进口唑吡坦片治疗失眠症的疗效和不良反应。方法：对32例失眠症患者随机分为两组，分别服用国产或进口唑吡坦。采用睡眠障碍量表（SDRS）、汉密尔顿焦虑量表（HAMA）、临床总体印象量表（CGI）和副反应量表（TESS）评定疗效和不良反应。结果：SDRS评定国产唑吡坦组减分率为49．7％，与进口唑吡坦组49．8％相近，主要不良反应为头痛、口干、便秘和出汗等，病人均能耐受。结论：国产唑吡坦治疗失眠症的疗效和进口唑吡坦相当。
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| 关 键 词： | 唑吡坦 睡眠障碍 疗效 治疗 |
| 修稿时间： | 2000年12月26 |
A double-blind investigation of zolpidem in the treatment of insomnia |
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| Zhang Honggeng,Zhao Jingping,Chen Yuanguang,et al..A double-blind investigation of zolpidem in the treatment of insomnia[J].Journal of Clinical Psychological Medicine,2001,11(3):146-147. |
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| Authors: | Zhang Honggeng Zhao Jingping Chen Yuanguang |
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| Institution: | Zhang Honggeng,Zhao Jingping,Chen Yuanguang,et al.Brain Hospital of Hunan,Changsha 410007 |
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| Abstract: | Objective:To compare the efficacy and adverse effects between home zolpidem (nuobin) and imported zolpidem in the treatment of insomnia. Method:32 patients with insomnia were randomly and double blindly divided into two groups.The efficacy and side effects were measured with sleep dysfunction rating scale (SDRS),Hamilton anxiety scale (HAMA),the clinical global impression scale(CGI) and the treatment emergent symptom scale(TESS). Results:According to SDRS,there were 49.7%,49.8% reducing rates inhome and imported zolpidem respectively.No statistical differences were found between two groups. Conclusion:The therapeutic efficacy of home zolpidem for insomnia is similar to that of imported zolpidem. |
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| Keywords: | Zolpidem Insomnia Efficacy |
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