芪术口服液药效学研究

目的:观察芪术口服液的免疫调节作用和抗应激能力.方法:采用环磷酰胺所致免疫功能低下小鼠模型,观察芪术口服液对正常和免疫功能低下小鼠的影响;用小鼠游泳法、常压耐缺氧法观察其对小鼠抗应激能力的影响.结果:芪术口服液能显著减轻环磷酰胺所致的小鼠白细胞、红细胞减少,提高脾脏指数、胸腺指数,提高小鼠RES吞噬功能,延长小鼠游泳时间及常压耐缺氧能力.结论:芪术口服液具有增强免疫力和抗应激能力的作用.

Study on Pharmacodynamics of Qizhu Oral Liquid

Objective: To observe the effects of Qizhu oral liquid(QOL)on the i mmunomodulatory and anti-excitability ability of mice.Methods: To observe th e effects of QOL on immunomodulatory ability of mice with normal and low immunom odulatory ability by the model that peritoneal injecting cyclophosphamide will d egrade the immunomodulatory ability of mice,and to observe the effects of QOL on antistiess ability of mice through the mice swimming method and against anoxia method under normal atmospheric pressure.Results:QOL will remarkably decrease th e mice's WBC and RBC reducing,increase the weight of their spleen and thymus,imp rove their RES' phagocytosis,extend the swimming time and the ability against an oxia method under normal atmospheric pressure.Conclusion: QOL could improve the ability of immune and anti-excitability of body.