前后联合入路治疗多节段腰骶椎结核的临床研究

目的探讨前后联合入路治疗多节段腰骶椎结核的干预方法及效果。方法将我院自2004年3月至2011年3月确诊收治的70例多节段腰骶椎结核患者随机分为2组，其中实验组38例行前后联合入路术，对照组32例行经前路病灶清除植骨融合固定术。随访2～3个月，采用Frankel分级评估脊髓神经功能损伤，并对比两组患者的总体健康（GH）、生理功能（PF）、生理职能（RP）、社会功能（sF）、情感职能（RE）、精神健康（MH）等生活质量指标变化。结果治疗后，患者的Frankel分级及生活质量指标均优于治疗前（P〈0．05），而两组间相比，实验组优于对照组（P〈0．05）。结论经前后联合入路手术治疗多节段腰骶椎结核，可显著改善患者的生活质量，减轻其脊髓神经功能损伤。

Clinical research on treatment of multi-segmental lumbosacral tuberculosis with the combined anterior and posterior approach

Objective To investigate effects and the combined anterior and posterior approach to the treatment of multi-segmental lumbosacral tuberculosis interventions. Methods 70 patients of multi-segmental lumbosacral tuberculosis were randomly divided into two groups. The experimental group patients （ n = 38） treated with the combined anterior and posterior approach. The control group patients （n = 32）treated with the anterior debridement. Follow-up for 2 - 3 months, using the Frankel grading system to assess the function of spinal cord injury,and compare the changes of the overall health of two groups patients （GH） ,the physiological function （PF） ,role physical （RP）, social function （ SF）, emotional functions （ RE）, mental health （MH） in the quality of life. Results After treatment, all patients with Frankel grade and quality of life are superior to those before treatment （ P 〈 0.05 ）. Comparing between the two groups, the experimental group were superior to the control group （P 〈 0. 05）. Conclusion The combined anterior and posterior approach to treat muhi-segmental lumbosacral tuberculosis can significantly improve quality of life for patient, and reduce the damage of spinal cord function.