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槐果碱及阿斯匹林对正常大鼠血浆PGI_2和TXA_2水平的影响
引用本文:钱月明,黄钺华. 槐果碱及阿斯匹林对正常大鼠血浆PGI_2和TXA_2水平的影响[J]. 中药药理与临床, 1990, 0(3)
作者姓名:钱月明  黄钺华
作者单位:第三军医大学药理教研室,第三军医大学药理教研室 重庆 630038,重庆 630038
摘    要:
槐果碱可明显升高正常大鼠血浆6-酮-PGF_(1a)含量,对TXB_2无明显影响。小剂量(1mg/100g)阿斯匹林轻度降低血浆6-酮-PGF_(1a)含量,但明显阻断槐果碱升高6-酮-PGF_(1a)的作用。

关 键 词:槐果碱  阿斯匹林  前列环素(PGI_2)  血栓素A_2(TXA_2)

Effects of Sophocarpine or/and Aspirin on Levels of ProstacAclin and Thromboxane A_2 in Blood Plasma of Rats
Qian Yue-ming Huang Yue-hua. Effects of Sophocarpine or/and Aspirin on Levels of ProstacAclin and Thromboxane A_2 in Blood Plasma of Rats[J]. Pharmacology and Clinics of Chinese Materia Medica, 1990, 0(3)
Authors:Qian Yue-ming Huang Yue-hua
Abstract:
After sophocarpine medication (i.p.), the level of 6-keto-PGF1a was markedly elevated in the blood plasma of rats, but that of thromboxane B2 was not altered. A. mild dose of aspirin (1mg/100g) could only slightly decrease the amount of plasmic 6-keto-PGF1a in rats, but greatly attenuated 6-keto-PGFia elevation of sophocarpine.
Keywords:sophocarpine aspirin prostacyclin thromboxane A_2  
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