加味益气丸联合驻春胶囊预防骨质疏松性椎体压缩骨折PKP后再骨折效果观察

目的 :观察加味益气丸联合驻春胶囊预防骨质疏松性椎体压缩骨折(OVCFs)椎体后凸成形术(PKP)后再骨折的效果。方法:87例OVCFs患者按治疗方法分为A、B两组。A组口服加味益气丸与驻春胶囊,B组口服碳酸钙D3片,两组均治疗6个月。比较两组术前、术后1年骨密度变化及再骨折发生率。结果:两组术后1年骨密度值均升高,与术前比较,差异有统计学意义(P0.05)。术后1年A组骨密度改善优于B组,差异有统计学意义(P0.05)。术后1年邻近椎体再骨折率A组14.2%,B组21.1%,两组比较差异有统计学意义(P0.05)。结论:PKP术后口服加味益气丸联合驻春胶囊,可提高骨质疏松患者骨密度,一定程度上可预防再次骨折。

Effect of Jiawei Yiqi Pill Combined with Zhuchun Capsule on Refracture after PKP for Osteoporotic Vertebral Compression Fractures

Objective:To observe the effect of Jiawei Yiqi pill combined with Zhuchun capsule on preventing refracture after percutaneous kyphoplasty( PKP) for osteoporotic vertebral compression fractures( OVCFs).Methods:A total of 87 cases of OVCFs patients were divided into group A and group B according to the treatment methods they choose. Patients in group A were given Jiawei Yiqi pill combined with Zhuchun capsule for oral administration. Patients in group B were given calcium carbonate D3 for oral administration.Both the two groups were treated for 6 months. The bone mineral density and the refracture rate of the two groups before treatment and 1 year after the PKP were compared respectively. Results:One year after the PKP,the bone mineral density value of the two groups were increased,which were statistically different from those before the PKP(P<0.05). The improvement of bone mineral density of group A was better than that of group B,with statistical significance(P<0.05). One year after the PKP,the refracture rate of group A was14.4% and the group B was 21.1%. There was a statistical significance between the two groups(P<0.05).Conclusion:After the PKP,Jiawei Yiqi pill combined with Zhuchun capsule can increase the bone mineral density of patients with osteoporosis and prevent refracture in a certain extent.