冠状动脉病变与2型糖尿病患者UAER的关系

目的采用320排动态容积CT（DVCT）评价冠状动脉病变范围与2型糖尿病患者24h尿白蛋白排泄率（UAER）之间的关系。方法采用320-DVCT对64例住院2型糖尿病患者进行冠状动脉成像检查,同时检测患者的UAER,根据UAER水平,将患者分为正常对照组,微量蛋白尿组和大量蛋白尿组。观察各组冠状动脉病变范围并加以比较。结果蛋白尿组冠状动脉病变范围比对照组明显增加（P〈0.05）。随着蛋白尿组UAER水平的增加,患者的冠状动脉病变范围明显增加（P〈0.05）。结论 2型糖尿病患者的UAER水平与冠状动脉病变范围有关,UAER水平越高者,其冠状动脉病变越严重。

Evaluation of association between the severity of coronary artery pathologies of 320-DVCT imaging and the UAER in type 2 diabetes mellitus

Objective To evaluate the relationship between the UAER and severity of 320-DVCT imaging of coronary artery pathologies in type 2 diabetes mellitus. Methods The 320 slice dynamic volume CT（320-DVCT） were done and urinary albumin excretion rate （UAER）in 64 eases of type 2 diabetic patients were measured. According to the level of UAER, all cases were divided into three groups：normal albuminuria group, mieroalbuminuria group and massive albuminuria group,The severities of 320-DVCT imaging of coronary artery pathologies in different groups were observed and compared. Results The coronary artery lesions in albuminuria group was much serious compared with negative control group （P〈0.05）. As the concentration of UAER increased,the number of stenosis of coronary artery increased （P〈0.05）. Conclusions UAER was positively correlated with the severity of coronary artery lesions. The higher of UAER level in type 2 diabetes mellltus is, the severer of the coronary artery lesion would be.