醒脑静治疗急性重度乙醇中毒的临床研究

目的:探讨醒脑静抢救急性重度乙醇中毒患者的临床治疗效果。方法:将72例急性重度乙醇中毒的患者随机分为醒脑静注射液治疗组(n=36)和对照组(n=36),醒脑静注射液治疗组应用醒脑静注射液治疗,其他治疗与对照组相同,对照组应用纳络酮治疗和常规治疗,观察两组患者神志恢复时间以及神志恢复正常时头痛、头晕症状。结果:醒脑静注射液治疗组和对照组神志恢复时间分别为(150±68.4)min和(260.3±92.5)min,差异有统计学意义(P<0.05);神志恢复正常后头痛、头晕、四肢无力等症状患者数分别为13.89%(5/36)和36.11%(13/36),差异有统计学意义(P<0.05)。结论:应用醒脑静注射液抢救急性重度乙醇中毒患者疗效显著,值得临床推广使用。

Clinical research on treating acute serious alcoholism by Xingnaojing injection

Objective To study the clinical effect of Xingnaojing injection in the treatment of acute serious alcoholism.Method The patients were randomly divided into two groups.The remedial group（n=36） was treated with Xingnaojing injection,naloxone hydrochloride and routine therapy;The control group（n=36） was treated with naloxone hydrochloride and routine therapy.Sober time and the sober-minded symptoms were observed.Results The sober time in the remedial group and the control group were（150±8.4） min and（102.3±10.5） min,respectively,and difference was significant（P0.05）.The sober-minded after treatment,patients still with symptoms such as headache,lighheadness and general fatigue were observed in 5 cases,accounted for 13.89%（5/36） in the remedial group and 13 cases,36.11%（13/36） in the control group（P0.05）.Conclusion Using Xingnaojing injection to treat acute serious alcoholism patients has a remarkable effect and is worth being used widely in clinical works.