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头孢哌酮/舒巴坦治疗老年患者下呼吸道感染的疗效与安全性
引用本文:许蕾,王笑歌. 头孢哌酮/舒巴坦治疗老年患者下呼吸道感染的疗效与安全性[J]. 中华医院感染学杂志, 2006, 16(10): 1157-1158
作者姓名:许蕾  王笑歌
作者单位:沈阳中国医科大学附属第四临床医院,辽宁,沈阳,110000
摘    要:目的评价头孢哌酮/舒巴坦治疗老年患者下呼吸道感染的临床疗效及安全性。方法86例明确下呼吸道感染>70岁的老年患者随机分为两组:头孢哌酮/舒巴坦组46例,1.0~2.0 g,静脉滴注2次/d;头孢哌酮组40例,1.0~2.0 g,静脉滴注2次/d,疗程5~14 d作对照。结果试验组和对照组的临床有效率分别为100%和80%,经统计学处理差异有统计学意义(P<0.05),不良反应率分别为4.98%和25.00%,差异有统计学意义(P<0.05)。结论头孢哌酮/舒巴坦适用于治疗老年患者下呼吸道感染性疾病。

关 键 词:头孢哌酮/舒巴坦  头孢哌酮  老年患者下呼吸道感染
文章编号:1005-4529(2006)10-1157-02
收稿时间:2006-01-16
修稿时间:2006-03-22

Efficacy and Safety of Cefoperazone/sulbactam in Treatment of Lower Respiratory Tract Infections of Elderly: A Clinical Study Compared with Cefoperazone
XU Lei,WANG Xiao-ge. Efficacy and Safety of Cefoperazone/sulbactam in Treatment of Lower Respiratory Tract Infections of Elderly: A Clinical Study Compared with Cefoperazone[J]. Chinese Journal of Nosocomiology, 2006, 16(10): 1157-1158
Authors:XU Lei  WANG Xiao-ge
Affiliation:The Fourth Hospitol, China Medical University, Shenyang, Liaoning 110000, China
Abstract:OBJECTIVE To evaluate the efficacy and safety of cefoperazone/sulbactam in comparison with cefoperazone in(treatment) of lower respiratory tract infections of elderly.METHODS Eighty six patients((>seventy) years old) with lung infections were equally divided into two groups:cefoperazone/sulbactam group and cefoperazone group in a regimen of 1.0-2.0 g,twice daily for 5-14 days.RESULTS The effective rate of both agents were 100% and 80%,and their ADRs incidence rate of elderly was 4.98% and 25.00%, respectively.There were statistically significant difference(P(<0.05)).CONCLUSIONS From results of this study it can be(concluded) that cefoperazone/sulbactam is an effective and safe drug for treatment of lung infection of elderly.
Keywords:Cefoperazone/sulbactam  Cefoperazone  Lower respiratory tract infection
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